Next-Generation Biotics

The Postbiotic Advantage:
Stability and Precision

For health-conscious consumers seeking to optimize their well-being, digestive health supplements offer various options. Postbiotics represent a scientifically validated advancement that combines stability, precision, and safety in one innovative solution.

Postbiotic Advantage

A Scientific Advancement

According to the International Scientific Association of Probiotics and Prebiotics (ISAPP), postbiotics are defined as preparations of inanimate microorganisms and/or their components that confer health benefits on the host.

Unlike probiotics, which rely on live bacteria, postbiotics consist of carefully inactivated microbial cells and their bioactive components.

Three Core Advantages

  • 1Greater stability across various temperatures and pH conditions
  • 2Standardized and consistent dosing
  • 3Enhanced safety profile
Advantage #1

Stability in Formulation

Storage requirements and shelf life depend on the preparation. Check the product specification for tested conditions and quality measures.

Temperature Resilience

Temperature Resilience

Storage requirements and shelf life depend on the preparation. Check the product specification for tested conditions and quality measures.

Ask which temperatures were tested
pH Stability

pH Stability

Tolerance to acid and other process conditions has to be measured for the ingredient and the finished product, not assumed from the category.

Test the intended process
Extended Shelf Life

Extended Shelf Life

Because the cells are not viable, loss of viability during storage is not a concern. Shelf life is still defined by the attributes measured for the ingredient.

Shelf life stated for the tested attributes and storage conditions
Manufacturing Flexibility

Manufacturing Flexibility

Formats under discussion include capsules, tablets, powders and functional foods. Confirm the processing conditions for each application.

Formats to discuss
Advantage #2

Precision Dosing

A standardised composition supports batch-to-batch consistency for the specified attributes.

Standardized Composition
Reproducible Results
Quality Assurance
Advantage #3

Safety Profile

Removing the risks that come specifically from administering live microorganisms

Inactivated microorganisms cannot replicate

Safety still needs to be assessed for the preparation, dose and intended population

No live-cell colonisation is required for the ingredient to act

Antibiotic resistance transfer via live cells does not apply; strain and preparation data should still be reviewed

Regulatory treatment depends on the market, the ingredient and the claim

Dose, composition and target population determine the safety assessment

Discover the Science Behind Postbiotics

This resource, informed by leading scientific consensus and peer-reviewed research, provides an evidence-based overview of postbiotics—what they are, how they function, and their documented health applications.

Explore Our Knowledge Hub

For comprehensive information on the scientific definition and mechanistic details